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Sanjeev Gangwar Selected Research

Therapeutics

1/2022Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
1/2019Uncialamycin as a novel payload for antibody drug conjugate (ADC) based targeted cancer therapy.
1/2018Adnectin-drug conjugates for Glypican-3-specific delivery of a cytotoxic payload to tumors.
1/2016Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations.
9/2003CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.

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Sanjeev Gangwar Research Topics

Disease

13Neoplasms (Cancer)
02/2024 - 09/2003
2Carcinoma (Carcinomatosis)
10/2020 - 09/2003
1Bites and Stings (Sting)
01/2022
1Ovarian Neoplasms (Ovarian Cancer)
10/2020
1Lung Neoplasms (Lung Cancer)
01/2019
1Hepatocellular Carcinoma (Hepatoma)
01/2018
1Renal Cell Carcinoma (Grawitz Tumor)
05/2013
1Leukemia
09/2003
1B-Cell Lymphoma (Lymphoma, B Cell)
09/2003

Drug/Important Bio-Agent (IBA)

11Immunoconjugates (Immunoconjugate)IBA
01/2023 - 05/2013
4Cytotoxins (Cytolysins)IBA
01/2020 - 01/2018
3AntigensIBA
10/2020 - 07/2014
2Peptide Hydrolases (Proteases)FDA Link
10/2020 - 09/2003
2MesothelinIBA
10/2020 - 01/2019
1Toll-Like Receptors (Toll-Like Receptor)IBA
02/2024
1InterferonsIBA
01/2022
1LigandsIBA
01/2022
1NucleotidesIBA
01/2022
11,2,3,4-tetrahydroisoquinolineIBA
11/2020
1BenzodiazepinesIBA
11/2020
1AntibodiesIBA
10/2020
1DipeptidesIBA
10/2020
1CarbamatesIBA
10/2020
1Surface Antigens (Surface Antigen)IBA
10/2020
1serum P-component (CIt)IBA
10/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1uncialamycinIBA
01/2019
1GlypicansIBA
01/2018
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2018
1Cysteine (L-Cysteine)FDA Link
01/2018
1Monoclonal AntibodiesIBA
07/2014
1MDX-1203IBA
05/2013
1Peptides (Polypeptides)IBA
09/2003
1ProdrugsIBA
09/2003
1N- (succinyl- beta- alanyl- L- leucyl- L- alanyl- L- leucyl)doxorubicinIBA
09/2003
1Metalloproteases (Metalloproteinases)IBA
09/2003
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2003
1EnzymesIBA
09/2003

Therapy/Procedure

5Therapeutics
01/2022 - 09/2003
1Immunotherapy
02/2024
1Drug Therapy (Chemotherapy)
01/2023